Use caution when administering Phentermine to patients with renal impairment. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. The amount of weight loss associated with the use of an anorectic drug varies from trial to trial, and the increased weight loss appears to be related in part to variables other than the drugs prescribed, such as the physician-investigator, the population treated and the diet prescribed. Highlighted below are the topics discussed at the meeting that OSMA is closely following. Take this medicine only as directed by your doctor. However in the presence of topiramate, Phentermine Cmax and AUC increase 13% and 42%, respectively. Succeed on your weight loss journey with our curated resources! While suffering from any of these health concerns may be a cause for concern, it does not mean a patient will not be able to use Phentermine at all. Doctors often combined the use of Phentermine with diuretics, thyroid hormone medicines and digitalis. For more FAQs, please see our full archive of Frequently Asked Questions about phentermine and related prescription appetite suppressants. The drug is classified under a certain chemical class known as amphetamine as it has a similar pharmacology value to other drugs classified in the class. Do not crush, break, or chew it. Keep from freezing. Ohio has some of the strictest rules in the country andthe current rules place time limitations on prescriptions that, many times, force physicians to stop a medication that is showing positive weight loss results. Therefore, coadministration of Phentermine and these drug products is not recommended. ). For oral dosage form (disintegrating tablets): Adults and children 17 years of age and olderOne tablet once a day, taken in the morning. The medication has been classified as a controlled substance in most countries and is also classified as a schedule IV prescription drug. All rights reserved. %%EOF Six years after the approval, a similar drug, called Aminorex, were released in Europe with the same purpose of helping obese individuals. Phentermine hydrochloride: Usual dosage is 8 mg 3 times daily (given 30 minutes before meals) or 15-37.5 mg once daily (in the morning). 0 Requirements may be altered [see Warnings and Precautions (5.9)]. Phentermine for weight loss - Mayo Clinic - Mayo Clinic - Mayo Clinic In order to use Phentermine, the doctor needs to prescribe the drug for a specific patient. Mayo Clinic does not endorse companies or products. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of Phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Is Phentermine a Controlled Substance? PDF label - Food and Drug Administration If we combine this information with your protected All rights reserved. After the tablet has melted, swallow or take a sip of water. Phentermine. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Read more here: How much does phentermine cost? Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. If you are a Mayo Clinic patient, this could A severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia. Phentermine may decrease the hypotensive effect of adrenergic neuron blocking drugs. The drug is classified under a certain chemical class known as amphetamine as it has a similar pharmacology value to other drugs classified in the class. Columbus, Ohio 43215 Phone: (614) 466-3934 Web: www.med.ohio.gov State Medical Board of Ohio 30 E . It should melt quickly. Follow your doctor's orders or the directions on the label. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); This website is a resource which lists doctors and clinics who may offer phentermine or appetite suppressants for patients they deem qualified. PDF What Every Pharmacist Needs to Know About Controlled Substances in Use caution in prescribing Phentermine for patients with even mild hypertension (risk of increase in blood pressure). ). Management of acute Phentermine hydrochloride intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. In patients with severe renal impairment (eGFR 15 to 29 mL/min/1.73m2), limit the dosage of Phentermine to 15 mg daily [see Dosage and Administration (2.2)]. Patients who have been on a Phentermine program should not suddenly stop using the drug. health information, we will treat all of that information as protected health endstream endobj 108 0 obj <>stream The most common brand of Phentermine is a product known as Adipex, but officially called Adipex-P. information submitted for this request. The following adverse reactions are described, or described in greater detail, in other sections: The following adverse reactions to Phentermine have been identified: Primary pulmonary hypertension and/or regurgitant cardiac valvular disease, palpitation, tachycardia, elevation of blood pressure, ischemic events. Medical Board Update - OSMA Although phentermine is the agent-of-choice among physicians specializing in obesity treatment, the use of this drug for obesity treatment by other physicians has long been curtailed because misapprehensions regarding phentermine safety. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. Review/update the Phentermine is intended to help overweight and obese patients who have already tried losing weight with diet and exercise. Phentermine Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. The drug has two primary functions in the human body, which is the reason why it is always accompanied by these lifestyle changes. The possibility of an association between valvular heart disease and the use of Phentermine alone cannot be ruled out; there have been rare cases of valvular heart disease in patients who reportedly have taken Phentermine alone. N;d0)zQ|,]8EtXy(En"GX omjU3Y3>kfkYHYi]-zhm{= o`i$G1BK%?9Z+(dm`mKt,?;6K@Q 7}}*Tw>7BkKsJ;E|Viexb T-3j%5QB%wI5'$5oB :h*C"Q7yjTzLO%6QS/u>HX 4DGz*A!1*p"7$-joX2YF8ht@\l[&LS$FU=udM&y.l_ Some preparations of the formula, however, have been classified as schedule II drugs. If the drug is taken too late in the day, it may also cause insomnia. Being extremely irritable and confused, or experienced unusual behavior or thoughts. Should the collaborating physician have restrictions on his/her ability to prescribe controlled substances including controlled substance weight loss medications, the CTP holder would be limited by the same restrictions.The administrative rules, Advanced Practice Registered Nurse Certification and Practice, contained in Chapter 4723-8, of Ohio Administrative Code (OAC), require all APRNs to utilize and incorporate into the nurses practice knowledge of Chapter 4731.,ORC, and rules adopted under that chapter by the State Medical Board that govern the practice of the nurses collaborating physician. It is impossible for them to complete the necessary physical evaluation (and follow-up) that is required to ensure that phentermine will not cause you undue harm. Some patients need to take the drug an hour before they eat breakfast, while others are advised to take it approximately one to two hours after breakfast. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Tak YJ, et al. Choosing a specialty can be a daunting task and we made it easier. However, weight loss clinics are not the perfect solution. While these are the most common side effects of the drug, they are not the only consequences associated with the intake of this medication. It can help weight loss by making you less hungry. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Biliopancreatic diversion with duodenal switch (BPD/DS), Endoscopic Sleeve Gastroplasty (Gastric Sleeve), Biliopancreatic diversion with duodenal switch. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The final option is online doctors who prescribe phentermine. Chapter 4731-11 - Ohio Administrative Code | Ohio Laws << /Length 5 0 R /Filter /FlateDecode >> The first use of Phentermine as a drug to help treat obesity dates back to 1938. If you take too much of this medicine, it may become habit-forming (causing mental or physical dependence). RPYcn@b[%XYK'Q %[.()GTkJ WCf.-i>n-oIzE*D40f#Gp'LcddmE8;>u?X"tO 1]M={4,ReC8E8Z Q1Lt$-XpFCrTJ Overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache, psychosis. The usual duration of treatment is 12 weeks or less. In some cases, the side effects were life-threatening and led to the death of a patient. Studies do not permit conclusions as to the relative importance of the drug and non-drug factors on weight loss. OSMA has historically had concerns with the limitations that these rules place on physicians who treat patients with obesity. Phentermine is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, amphetamine (d- and dll-amphetamine). In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Phentermine is a schedule IV drug that requires a consultation with the doctor and a prescription. Here are the results of a recent poll that asked current phentermine patients where they received their phentermine prescription ( The promotion of this brand as a diet pill started in 1990. Cardiovascular effects include arrhythmia, hypertension or hypotension, and circulatory collapse. Many physicians who currently receive the reports have found that the reports help them better understand, and possibly alter, their prescribing practices. These include, but are not limited to:Whether the care and treatment of obese patients and weight management is new to the APRNs existing practice, and whether this aspect of practice is within the APRNs national certification and patient population specialty, meeting the scope of practice requirements in Section 4723.43, ORC. Phentermine hydrochloride, an anorectic agent for oral administration, is available as a tablet containing 37.5 mg of Phentermine hydrochloride (equivalent to 30 mg of Phentermine base). The medical boards ICD-10 Committee is tasked with reviewing ICD-10 data that physicians submit to the OARRS system when prescribing controlled substances. For oral dosage form (extended-release capsules): Adults and children 16 years of age and olderOne capsule once a day, taken before breakfast or 10 to 14 hours before sleeping. Special Populations Geriatric Patients Select dosage with caution, starting at lower end of dosage range. Even patients who are overweight and pregnant at the same time are not allowed to use this product. Today, Phentermine can still be obtained through the doctors prescription in the majority of countries around the world. As phentermine is similar to amphetamine, it is a controlled drug (class C5) and has the potential for abuse. allnurses is a Nursing Career & Support site for Nurses and Students. Phentermine Monograph for Professionals - Drugs.com | Prescription Drug